Faculty of Virology
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George Stoica
Professor
Veterinary PathobiologyEducation:
DVM Institute of Agronomy, Yassy-Romania 1966
M.Sc. Ohio State University 1982
Ph.D. Michigan State University 1984
Research Description:
Mechanism(s) of immuno-neurodegeneration induced by Moloney murine leukemia virus, temperatue sensitive mutant 1 (MoMuLV-ts1) in mice; an animal model for human neurodegenerative disorders and AIDS.Representative Publications:
Yu, Y. E., Stoica, G., Multani, A.S., Zhang, W., Pathak, S., and Wong, P.K.Y. Characterization of a transgenic-induced mutant mouse line which showed thymus atrophy and neuronal degeneration. Mouse Genome, 95:704-706, 1997Wonkyu Choe, G.Stoica, William Lynn and P.K.Y. Wong. Neurodegeneration induced by MoMuLV-ts1 and increased expression of Fas and TNF-a in the central nervous system. Brain Research, 779, pp 1-8, 1998
Kaushik Datta, Anita Chin, Tamar Ahmed, Wei-Guo Quing, K. Leslie Powell, P. Simhambhatla, Michael C. MacLeod, George Stoica and James P. Kehrer. Protection against cyclophosphamide-mediated bladder and lung toxicity in mice by 2,6-ditihiopurine. Toxicology, 125(1):1-11, 1998.
Stoica G., Barker R., Lynn W. S., and Wong P.K.Y. Quantitative variation of free amino acids in the central nervous system of MoMuLV-ts1-infected mice. In Vivo, 12:395-402, 1998.
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